The headword, evidently extracted from somewhere, but first attested in this form at Themistius, Paraphrase of Posterior Analytics, 5.1.60, is a feminine noun in the nominative singular. It is registered in the Supplement to the LSJ, where it is given as a later alternative spelling of siku/a (bottle-gourd); see generally LSJ s.v., which identifies this plant as Lagenaria vulgaris (Tutin, p. 298).
[Adler, also citing the Lexicon Ambrosianum, reports in her critical apparatus that the editio princeps of the Suda transmits the lemma as *siku/a. She also notes that this entry and sigma 400 are in reverse order.]
[1] The gloss is the nominative plural of the neuter noun tetra/ggouron, large cucumber; see generally LSJ s.v., which cites this Suda entry as its source, and ps.-Herodian, Partitiones 124.1. [Adler reports that ms M reads tetra/gkoura; also that ms M inserts above the entry to\ par' h(mi=n lego/menon a)griaggou/ria (what amongst us are called a)griaggou/ria).]
[2] Gourds, horns, and ceramic and metal vessels were used as cupping instruments in ancient medicine (Milne, pp. 101-105); cf. kappa 2574.
[3] This secondary lemma is a neuter noun in the nominative/vocative/ accusative singular; see generally LSJ s.v. [In her critical apparatus Adler reports that mss AF omitted this addendum, though ms A (Parisinus 2626) added it in the margin.]