The headword, evidently quoted from somewhere, is the neuter nominative/accusative singular of the adjective xeiro/hqhs (literally "accustomed to the hand"), a compound of xei/r ("hand") and h)qa/s ("accustomed to").
[1] = Etymologicum Genuinum, Etymologicum Magnum 810.39. See also Hesychius and ps.-Herodian 150.
[2] = Lexicum Ambrosianum 144 (according to Adler). These two words are the masculine/feminine nominative singular and masculine/feminine genitive singular of the adjective, demonstrating the paradigm.